The Royals are now long odds-on with the bookmakers to make a quick return to the Championship, but McDermott has reassured the club's fans he is doing everything he can to avoid relegation.
"It's not about me it's about the club," said McDermott after his side had slumped to a fourth successive Premier League defeat.
"I thought the fans were fantastic at the start of the game. The fans want to see their team win.
"We've had a lot of good days in the past three years. The past three weeks have been difficult. The fans just want to see the team win.
"Once March is out of the way - we play Manchester United away and Arsenal away - then we have seven games. We'll see where we are at the end of March and go from there.
"It won't be hard to pick ourselves up. You have a choice you either give up or you get back on and have a right go at it.
"That's what we've done. We'll pick ourselves up and move on quickly. It's not over until the middle of May."