Spurs face Manchester City on Sunday, with the same fixture last term proving one of the most entertaining of the season - Mario Balotelli scoring a late penalty minutes after Jermain Defoe came agonisingly close to giving Spurs a 3-2 lead.
And Walker is confident Villas-Boas is the man to take the club back into Europe's elite competition after their relegation to the Europa League last term.
"With the players we have and the players we brought in, I am more than confident (we can finish in the top four)," said Walker.
"We just need to keep listening to the gaffer and his tactics. If we do that then I most definitely think that we will get the results we need.
"It was disappointing how it went last year but that's just the way it goes."
Tottenham were defeated 1-0 at the hands of Wigan last weekend with some claiming the Portugese boss is not up to the job.