Both men have been heavily linked with moves to the Premier League during the winter transfer window.
Congolese striker Mbokani, who has rediscovered his form since returning to Belgian football, is said to be interesting Liverpool, Norwich, Southampton and Tottenham, while Argentine midfielder Biglia has attracted admiring glances from Arsenal.
Anderlecht are reluctant to part with any of their key men midway through the 2012/13 campaign, but concede that deals could be done in the summer.
Chairman Roger Vanden Stock told the club's official website: "Mbokani says he will remain until the summer. We have agreed that he can leave in June.
"I can only see things changing if he has the chance to go and play in the Champions League. He would knock back the likes of Southampton and Norwich.
"English clubs have seen what (Christian) Benteke is capable of and they know that Dieu is even better. A transfer fee of €10million (£8.5m)? I think it would be closer to €20million (£17m)."
He added: "We will also work on the transfer of Biglia. We are pleased that no-one has met his asking price. We want to win the title and Biglia can be of use to us.
"But I don't want to hold a player against his will. We are coming towards the end of a cycle and in the summer Mbokani and Biglia could leave."