Liverpool ended their 12-match unbeaten Premier League run when a late Steven Gerrard penalty sealed a 3-2 win at Anfield.
Defeat dented third-placed Spurs' hopes of increasing their lead over Chelsea and Arsenal in the race for a spot in Europe's elite competition.
But the boss remained optimistic, telling Sky Sports: "A couple of mistakes at the end cost us the game but we can't be too negative on what we have done.
"Hopefully this is a reminder for us but we'll try and go on another 12-game unbeaten run.
"The chance for (Gylfi) Sigurdsson (to make it 3-1) was a big, big chance. But we did ever so well to come into the game, played well and managed to create some good opportunities. But we couldn't control the game in the manner that we should have.
"The boys did well apart from a couple of mistakes that we committed. But that was a good performance. We are confident we can put our strengths back together and go on another run.
"We've suffered set-backs before. But we've jumped out of them and I think that it's a wonderful opportunity for us to put ourselves back on track."