Spurs have spent much of the 2012/13 campaign in and around the UEFA Champions League places.
They have, however, slipped to fifth over recent weeks - two points adrift of fourth-placed Arsenal with a game in hand.
Holtby is determined to ensure that Andre Villas-Boas' side do not miss out on a seat at European football's top table, with six crucial fixtures awaiting them.
He told the Evening Standard: "We're a strong side and when we play at home, most teams come here with the intention of holding their defensive line, keeping it tight at the back and trying to play on the break.
"When a team comes to attack us, it means we can play even more on the counter-attack, especially with the pace we have up front.
"I have big faith in us because we have a quality side.
"We have players like Gareth (Bale) and Aaron (Lennon) to come back who haven't been there in recent matches. As a team, we just have to try not to concede some of the goals that we've let in during recent matches."
He added: "The games against teams like Southampton and Sunderland are ones we have to win.
"We have to get those points to stay up there. After 38 games, we have to be in the top four.
"If you look back at the season and see the effort we have put in, I think we deserve to finish there but we have to get the points and make sure of it."