Harry Redknapp is set to take charge of struggling Rangers for a home game for the first time, but Lambert is aware that a Villa win will lift them 11 points clear of the Premier League's basement club.
Lambert, whose side have collected four points from their last two games at home to Arsenal and Reading, said: "Harry going in there will automatically give them a big lift because he is a brilliant manager.
"Everyone knows what Harry can do from the clubs he has been at during his career.
"QPR have an abundance of really good players, the crowd will be buoyant and will get behind him. You wish him well - but after Saturday.
"The pressure is on QPR to make the running but we are definitely a threat, that's for sure.
"We would be happy to win the game for ourselves and keep them down there.
"We are certainly playing well enough to go and win. We are only a few points off mid-table. It is so tight in the bottom half of the table."
Lambert has great faith in Villa's crop of youngsters and they fielded their most inexperienced Premier League line-up against Reading in midweek with an average age of 23 years and 324 days.
Striker Christian Benteke has been grabbing plenty of headlines for his goalscoring feats including the late headed winner against the Royals.
But Lambert has also been pleased with the impact of former Crewe midfielder Ashley Westwood, another of his summer signings.
Lambert said: "We have a really young team, our youngest side in the Premier League since it started, which bodes well for the future.
"The young lads have been exceptional since Sunderland. I couldn't ask for any more from them. We had a tough run with the two Manchester clubs and Arsenal.
"Benteke has been unbelievable for us and Ashley Westwood has been absolutely terrific. People like Ashley are maybe not getting the credit they deserve.
"He is playing unbelievable football, he never gives it away and that's from a young lad who has just come from Crewe. He's slotted in so well and stayed in the side."