Saturday's 4-1 defeat at the hands of Swansea was another disappointing result for Villa, who have taken one point from their last six matches and are just four points above the drop zone.
With Villa facing daunting trips to Manchester City and Tottenham in their final two matches this season, Lambert was keen to underline the importance of their final home match of the current campaign.
"Next week's game (against Hull) is a cup final," he said.
"That's it, in a nutshell.
"But if you ask any football person - if your destiny is in your own hands, you take it. You don't want to rely on anybody else."
Despite the heavy loss, Lambert's counterpart Garry Monk thinks Aston Villa have the quality to stave off the threat of relegation this season.
"On this evidence, I think yes (they will beat the drop), he said. "Obviously, they'll be disappointed with the result, but you could see enough fight and quality.
"After the first goal for us, when we went one up, I think for the next 15, 20 minutes they showed what they can do and they had some very good opportunities.
"I think we defended well in that period and stayed in the game, conceded just the one goal which was disappointing, but I can see more than enough for them to survive."
The result lifted Swansea to 12th in the table and Monk hopes they can build on the result in their final two games of the season.
"For us, it's been a disappointing season overall," he said. "The standards haven't been there, we've been a little bit inconsistent but we want to finish strongly and that's the message we try to put out in the last few games.
"Hopefully, in the next two games we can do that and really finish the season on a positive."