Recent fixtures have seen the champions claim a last-gasp win at home to Reading before suffering a one-goal defeat to Sunderland at the Stadium of Light.
The Blues head to Carrow Road on Saturday, then host Stoke City three days later to conclude a run of games that could go a long way to deciding their fate this season.
"It's unusual to play so many matches in quick succession; in Spain there's a brief recess at this time," said Aguero.
"But, each country has its own traditions and it's just a matter of getting used to it. There are no worries on that score."
The 24-year-old Argentine, whose late goal clinched City's first title in 44 years last May, reflected ruefully on the trip to Sunderland that ended in a third consecutive defeat on Wearside for the Blues.
He added: "Our game at Sunderland wasn't great but we didn't deserve to lose. We have to keep working to get ourselves back to our best form and keep our ambitions in sight."
The defeat at Sunderland, courtesy of a goal from former City winger Adam Johnson, was the first time City had lost in 15 Premier League fixtures where Aguero and Carlos Tevez had both started for the Blues. It is a trend that the former Atletico Madrid striker is keen to return to as soon as possible.
"I didn't know about that statistic. Those are good numbers, aren't they? I hope each time we play together we can keep that average. But it is not about Carlos and me," he said.
"Beyond who is on the field, the important part is that we all work together for the same goal, because what we all want is to defend City's title. For that we need everyone playing well and to start winning again straight away."