The Ivory Coast international was substituted at half-time during last weekend's draw at Swansea and was rested for the midweek home win over West Brom.
But those were precautionary measures and Toure, who scored the winner in the 2011 FA Cup final win over Stoke City, has declared himself fully fit.
The 29-year-old said: "I am good. Sometimes it is difficult to play all the games at the same level and sometimes you can get an injury.
"But we have worked on that, trying to keep injury far away and try to concentrate on delivering at the weekend.
"I am already fit. I started training three days ago and I am well in now.
"I want to deliver a good game and help the team to achieve something important."
Winger Scott Sinclair has been ruled out after undergoing surgery to remove a blood clot in his shoulder but otherwise City have no injury concerns.
Costel Pantilimon is expected to be selected ahead of England goalkeeper Joe Hart after playing in all the previous rounds.
James Milner said: "We are bitterly disappointed how the league went this year.
"The main thing is that we win a piece of silverware at the weekend, do that and take the momentum of winning a trophy into next season and have a good league campaign."