Sandy Stewart has been confirmed as assistant manager, having worked closely with Coyle at Bolton, Burnley and St Johnstone, while former Latics keeper Phil Hughes becomes the club's new goalkeeping coach.
Andy Mitchell joins as head physiotherapist and James Barrow, whose father Graham remains in the post of first team coach, takes up a role as strength and conditioning coach.
"It was so important that we brought in the right personnel to take up key roles at the club and I'm delighted to bring in people who have proven themselves at the highest level and who I trust completely," Coyle said of the quartet, who all worked together at Bolton.
"I know they'll come here and do everything in their power to bring success to Wigan Athletic, and I can't ask any more than that."
Dennis Lawrence will remain as development squad coach but Graeme Jones, Richard Evans, Iniaki Bergara and Kevin Reeves have left the club.