The Latics, now managed by Owen Coyle following Roberto Martinez's departure to Everton, were relegated from the Premier League last season while the Red Devils cruised to the title - but Boyce insists the fixture holds no fear for the underdogs.
The 33-year-old said: "Because we have so many different players here we haven't had time to think about relegation. We know what we need to do. The chairman has told us what he expects and the manager is the same.
"As players we want to get back in the Premier League and the new players would only have come here if they thought the club would go up.
"I don't feel less of a player. We all have our own personal goals to achieve and that is to be back in the Premier League.
"To play against Manchester United so early will show us how far we need to go to put our mark down in the Championship. It will be a massive game to show we can compete at that level.
"There is no real pressure. This is how we are going to test ourselves to see how good we actually are against the champions of England."