Sam Allardyce’s side beat Spurs home and away last season, and also knocked them out of the Capital One Cup, so will hope for more of the same before visiting Crystal Palace in their second game.
September brings games at home to Liverpool and away to Manchester United before October starts with another London derby as old boss Harry Redknapp brings promoted Queens Park Rangers to Upton Park.
Christmas serves up back-to-back London derbies for West Ham as a trip to Stamford Bridge on Boxing Day is followed by the visit of Arsenal two days later.
New Year’s Day will see West Brom make the trip down to Upton Park before the end of February and start of March offers four derbies in a row against Spurs, Palace, Chelsea and Arsenal.
West Ham’s final home game of the season is against Everton on May 16 before the campaign concludes on May 24 with a trip to Allardyce’s former club Newcastle United.
Opening three games:
August 16 - Tottenham (h)
August 23 - Crystal Palace (a)
August 30 - Southampton (h)