Tottenham are desperate for victory as they chase a place in next season's Champions League.
Sunderland are already safe - thanks to Wigan's defeat at Arsenal on Tuesday - but the Black Cats boss insists that does not mean they travel with nothing to play for and the Italian does not want to finish the season fourth from bottom.
Di Canio had hoped they would seal their top flight status by beating either Stoke or Southampton in consecutive home games, but both ended 1-1, meaning victory for Wigan at the Emirates Stadium would have set up a tense final day.
But while the pressure of the relegation fight may have gone, there will be no let-up from the manager.
The 44-year-old said: "We still have one game to go and we have to make sure that we are going to perform well because I don't want to finish fourth from the bottom if it's possible.
"With even a draw, potentially we can be sixth from the bottom. But we have to make sure that we are going to put everything into this game and not finish fourth from the bottom."