O'Shea is part of a 27-man squad for Friday's friendly with Latvia in Dublin and the trip to Poland four days later.
He played for O'Neill at Sunderland and alongside Keane at Manchester United and admits their appointment has given him something to look forward to.
"I am looking forward to next week," said O'Shea ahead of O'Neill's official unveiling at a press conference in Dublin later on Saturday.
"I can't wait. It has got the excitement back for the public and the players should be looking forward to working with two inspirational characters.
"I know both of them very well and if they have spoken to each other beforehand and decided they want to go forward together, it can only be good really.
"I had spoken a couple of times to Martin who said he had spoken to Roy during the TV work they had done together in the past so I knew the type of ideas they both had and that they enjoyed their conversations.
"I knew that was never going to be as big an issue as people have made out.
'It can only be good because of the type of personalities they are in terms of winning mentality, drive, hunger and motivation - all those things are needed for us to get going again for qualifying for tournaments again and giving a boost back to the fans as well.
"Roy is arguably Ireland's best ever player so having him in the dressing room for the younger lads and older lads to look up to and thinking that he is on our side wanting us to win.
"And we have Martin's experience. He will be the boss, he is the main man and we will be guided by him and the team he has in place and from knowing the two men and having them on our side it is going to be brilliant."