The Wales international has not played a competitive match since the 0-0 draw with Sunderland back in April 2012 due to a cruciate ligament injury but he could move a step closer to a return to action with a run-out against the Dragons.
"He'll get a great reception at Wrexham but also from the Wolves fans because he's been a very popular player," manager Kenny Jackett told the Daily Post.
"And people will be with him because he's had 16 months out injured and no one wants to see that.
"He does seem to be fine and he speaks very confidently and trains very confidently at present, so that's nice to see and I hope that continues now.
"He's had a good pre-season and in terms of training, he's done every session last week - even working with the strikers before the games he has been throwing himself around."