Kenny Jackett's men cruised to the League One title last season with a record points haul, and their reward for promotion is a testing first game against relegated Norwich City on the opening weekend.
Their first away game of the new campaign comes against fellow promoted side Rotherham United on the 16th, while a trip to another relegated side, Fulham, awaits four days later.
A home game with Brighton kicks off the Christmas festivities for Wolves, with games against Watford (h) on Boxing Day and League One runners-up Brentford (a) two days later.
Wolves' return to the second tier also means that their Midlands rivalry with Birmingham is continued. Wolves will play host to Blues on November 1, while a trip to St Andrew's awaits on April 11.
Jackett will make his return to former club Millwall on the last day of the season on May 2, following a tough April involving games with Nottingham Forest, Leeds, Birmingham, Middlesbrough, Ipswich and Wigan.
Opening three games:
August 9 - Norwich City (h)
August 16 - Rotherham United (a)
August 20 - Fulham (a)