The Royals arrive at the Britannia Stadium in 17th position in the Premier League, seven places below the Potters.
But the respective clubs' league positions are not a reflection of current form, with Stoke searching for a first win since a 3-1 victory over Liverpool on Boxing Day.
Brian McDermott's Reading have dropped just two points in their last four league outings, largely thanks to a flurry of late goals which Pulis believes is a reflection of the belief in the side.
"We have to get some points and we are keen to get back to winning ways," Pulis said.
"We have had a very, very tough run again like at the start of the season, we have got through that period and we are still 10th in the league so we are pleased with that.
"What we have to do now is win a few games, although we know it will be tough (on Saturday) - they are on a great run at the moment.
"What they have shown by scoring so many goals late on is that they have real spirit in the team. It has been remarkable really.
"Brian will be really pleased with the belief the team has shown - it has given them great heart, I'm sure."