Sky Bet will now deliver the matchday betting operation and feature heavily across all of the club's digital marketing and broadcast platforms and receive high profile TV branding at the stadium, extensive engagement opportunities with the club's fanbase and advertising across all matchday media and on the club's own LUTV channel.
Under the new agreement the West Stand will also see significant branding installed for the Sky Bet brand.
Leeds United Managing Director David Haigh said: "We are delighted to welcome Sky Bet into the Leeds United Commercial Partners programme which continues to grow from strength to strength.
The Sky Bet brand is one of the most high profile, fastest growing brands within its sector and we are proud to be the first direct football club partnership with Sky Bet.
"The new partnership also means that all four stands here at Elland Road will be sponsored for the first time ever as we continue to attract high calibre sponsors to the club. It's also great news for the City as two of the major organisations will be working together.
We are confident that Leeds United fans will be able to take advantage of some of the great betting odds that Sky Bet will offer."
Richard Flint, managing director at Sky Bet, said: "We're delighted to be partnering with Leeds United as the club's official match-day betting partner for the 2013/14 Championship season.
"In addition to providing in stadium match day betting for fans, our trading team, many of whom are big Leeds United supporters, are really looking forward to working with the club to provide quality betting content for the Leeds United website using their knowledge and passion for the club.
They'll also be creating exclusive markets that fans will be unlikely to find with any other betting sites or bookmakers.
"This is the first football club Sky Bet has ever partnered with and it's a fantastic opportunity for two Leeds-based companies to work together to provide fans with up-to-date market options and exclusive promotions.
"We're excited to work with Leeds United over the coming season to ensure that the offer and service we create for the club's fans continue to develop over time."
You can also get 13/2 for the Yorkshire club to be promoted and 11/4 for a top-six finish in addition to a vast range of specials.