The Shakers wasted a host of chances early in the match before strikes from Jimmy Smith and David Mooney sealed the points for play-off chasing Orient, leaving Bury seven points from safety.
Blackwell stated: "Within one minute 48 seconds of the kick-off, we had two chances that you dream for and it's getting like a cracked record reflecting on the chances we've missed.
"I'm pleased with the team because they've given it everything and looking at the two sides, you wouldn't have known who was top and who was bottom.
"I thought that it was a very good away performance but the only thing that was missing was the goals.
"We must have had eight chances but it's the same story over again, what can I say and if you miss chances like we did, you can't win games, it's as simple as that.
"We've missed crystal-clear chances in so many games this season, chances that you dream about as a striker.
"If we could have finished this season, we'd be in the top 10.
"Goals change games, they change the mentality of the game, the pace of the game and we had the opportunity to put the game to bed in the first five or 10 minutes.
"Even in the second-half, their keeper has made two great saves and we've missed two or three good chances. We were terrific but the only person in our club who is happy is our groundsman because he's found a pitch worse than his."