The Nigeria centre-half would cap a memorable first season if Celtic beat Hibernian at home and Motherwell lose to St Mirren at Fir Park.
Celtic allowed the Buddies to rescue a 1-1 draw in Paisley after Victor Wanyama's red card and Ambrose, who moved to Glasgow on transfer deadline day, August 31, from Israeli Premier League side FC Ashdod, told the Celtic View: "We came back for the (St Mirren) first game after representing our countries and it takes a little bit of time.
"But everyone will train a little bit together again and we will come back to where we were before.
"In football it doesn't always go the way you planned. It can go in an ugly way and sometimes it can go in a good way.
"The most important thing is for us to keep our heads straight and our aim on the championship, work harder and prepare well.
"On some days, you have a bad day and win and there are days when you play fantastic and lose - this is football. You just have to accept it and move on."
On Wanyama's dismissal, Ambrose, who won the Africa Cup of Nations with Nigeria in South Africa at the start of the year, added: "It was harsh as Victor knows as a midfielder - it's his job to win the ball - that's his role in the midfield.
"I believe the tackle wasn't a red card. And the penalty was outside the box. Everybody saw that, so we were complaining to the referee. If he wanted to give a foul, it should be a free-kick not a penalty as it was outside.
"But again, we can't change his judgement, so we just have to keep working hard and preparing for the next game."