Zlatan Ibrahimovic scored his fifth Ligue 1 brace of the season as PSG restored their eight-point lead with a 2-0 win over the Greens.
Two first-half strikes from the champions' top scorer were enough to secure Blanc's men their seventh straight win and maintained their impressive lead over second-placed Monaco, who got past Lyon 3-2.
Earlier this week, the French giants saw off Bayer Leverkusen with a 6-1 aggregate victory to progress to the UEFA Champions League quarter-finals, following a 3-0 league win at Bastia last weekend.
Blanc was delighted his men kept the goals coming and told his club's official website: "All victories are important. We aim to win every single home match so it's mission accomplished.
"We had three matches in the last seven days, which is not easy to manage, and we recorded three wins over Bastia, Bayer Leverkusen and now St Etienne, another quality opponent, technically very good and courageous.
"Winning 2-0 is an excellent thing and a great way to cap off a very good week."
Ibrahimovic took his league goal tally to 35 for the season and was pleased to move past Carlos Bianchi's record when he was top scorer at the club in the two seasons from 1977-1979.
The Sweden international said: "This was a very important match for us and we won together, as a team, so it's another step towards our objective.
"We played well and scored two goals.
"I am very happy to have beaten Carlos Bianchi's record (40 goals for Paris in a single season) but I owe it all to the team and I thank them, like I do all the supporters at the Parc des Princes."
PSG travel to mid-table Lorient in their next match on Friday - the same day they will find out their opponents in the Champions League quarter-finals, with the matches to be played on April 1 and 2.