Celtic and Barca meet on 1 October in Group H - with the Catalan club hoping to avenge their 2-1 defeat against Neil Lennon's men last November.
The group of former European champions also includes AC Milan and Ajax, but Messi is anticipating another special night at Celtic Park.
Messi said: "I've been fortunate to play in some great stadiums in Europe with Barcelona but none compare to Celtic.
"The atmosphere their fans create make it a very special European night of football.
"I'm very excited to play at Celtic again in the group stages. Of course the last time we played in Scotland it was not a good result for us, but next time we will be looking to win.
"It's the most competitive group and we know we can't take nothing for granted."