The Colombian made over 30 appearances for Inter last season and has been linked with Tottenham Hotspur in recent weeks.
But, Guarin says that he will still be with the Serie A side next season.
Speaking to Total Futbol, he said: "I won't be leaving, I will be staying at Inter.
"I still have a lot to learn and I only joined Inter about a year ago. Inter are a great club with a great squad. I am playing my football in Milan with the intention of making history."
Inter president Massimo Moratti has also had his say on Guarin's future.
Speaking to Inter.it, he said: "It's good that he says he will stay. There are a number of clubs interested in him but he is one that we want to keep."