The 27-year old has been linked with a number of Premier League sides in the past, with Manchester City, Newcastle, Tottenham and Arsenal all reported to have been tracking him.
However, Serie A appears to be Biglia's chosen destination and the Argentine says it is the right time for him to move on.
"The moment of taking another step has arrived. I have talked to about this with Anderlecht. There is a nice offer from Italian football," he told Abriendo Juego.
"I have been at this team for seven years. It's the moment for changing and at Anderlecht they agree with this."