Bender was part of coach Joachim Low's original squad selection for Friday's 3-0 victory away to Kazakhstan, but withdrew due to flu.
He will now fill in for Bastian Schweinsteiger in the return meeting with Kazakhstan in Nurnberg after the Bayern Munich midfielder picked up a yellow card to earn a suspension.
Bender has just three caps, but can expect a fourth on Tuesday night due to a shortage of options in the defensive midfield area.
The condition of Julian Draxler is also being monitored after he left the field due to concussion, being replaced by Lukas Podolski, who could therefore start the reverse fixture.
Meanwhile, striker Mario Gomez remains a doubt after missing out due to a thigh strain he picked up in training, leaving Low still without a recognised striker in his squad.
"The important thing is our attacking midfielders push up into that position," said Low to ZDF television. "It worked quite well."