Dortmund are already resigned to losing Mario Gotze to arch rivals Bayern Munich at the end of the season, while star striker Robert Lewandowski could follow him out of the door with numerous clubs coveting the Poland international.
Centre-back Mats Hummels is another Dortmund player who is attracting plenty of interest, with Barcelona reportedly looking at the 24-year-old as the Spanish giants look to strengthen at the back.
Reus has also been the centre of transfer speculation himself but the 23-year-old is hoping Dortmund manage to keep their "family" intact.
He told Spanish newspaper AS: "I hope that no player leaves Dortmund, not Hummels, not anybody.
"We are a family and we have contracts. The atmosphere in the dressing room is very good and we feel very good at the club and in the city."
Regarding Hummels, Reus believes his fellow Germany international is going to become one of the top defenders in the game.
"In the next few years he will be world class, but even now, despite his age he already has experience.
"He can create attacks with his great vision at the back and, in case anyone forgets, Hummels is also good in the opposition penalty area, which makes him the complete player."