Triple H will not only be looking for revenge for his SummerSlam defeat to Lesnar, who returned to the WWE after an eight-year hiatus in April, but he will also be hoping to save his in-ring career, which will end if he loses to his bitter rival inside New Jersey's MetLife Stadium.
The Game and The Beast have acquired sterling résumés during their time in the WWE, winning multiple championships and important matches, and ahead of their much-anticipated 'Mania showdown on April 7, skysport.com looks at both competitors' vital statistics...
Nicknames: The Game, The Cerebral Assassin, The King of Kings
Finishing move: Pedigree
Height: 6ft 4in
Weight: 255 lb
Entrance music: The Game by Motörhead
WWE main roster debut: 1995
Titles held: WWE Championship (8 times); World Heavyweight Championship (5); Intercontinental Championship (5); WWE Tag Team Championships (3); European Championship (2)
Other accolades: 1997 King of the Ring; 2002 Royal Rumble winner
Notable rivals: The Undertaker, Shawn Michaels, Kurt Angle, Randy Orton, Batista, Mick Foley
WrestleMania record: Seven wins, nine losses
WrestleMania victories: Goldust (WrestleMania 13); Owen Hart (WrestleMania 14); The Rock, Mick Foley and The Big Show in a Fatal Four Way (WrestleMania 16); Chris Jericho (WrestleMania 18); Booker T (WrestleMania 19); Randy Orton (WrestleMania 25); Sheamus (WrestleMania 26)
WrestleMania losses: The Ultimate Warrior (WrestleMania 12); Kane (WrestleMania 15); The Undertaker (WrestleMania 17); Chris Benoit in a Triple Threat Match that also included Shawn Michaels (WrestleMania 20); Batista (WrestleMania 21); John Cena (WrestleMania 22); Randy Orton in a Triple Threat Match that also included John Cena (WrestleMania 24); The Undertaker (WrestleMania 27 and WrestleMania 28)
Recent WWE matches: Submission defeat to The Undertaker at WrestleMania 28, submission defeat to Brock Lesnar at SummerSlam
Achievements outside WWE: Triple H also has many acting credits to his name and starred alongside Wesley Snipes and Kris Kristofferson in 2004 action movie Blade: Trinity, while he also featured in 2011 kids film The Chaperone
Nicknames: The Pain, The Beast, The Freak, The Anomaly, The Psycho Viking
Finishing moves: F-5, Kimura Lock
Height: 6ft 3in
Weight: 266 lb
Entrance music: Next Big Thing by Jim Johnston
WWE main roster debut: 2002
Titles held: WWE Championship (3 times)
Other accolades: 2002 King of the Ring; 2003 Royal Rumble winner
Notable rivals: Kurt Angle, Eddie Guerrero, The Undertaker, John Cena, Big Show, Goldberg
WrestleMania record: One win, one loss
WrestleMania victories: Kurt Angle (WrestleMania 19)
WrestleMania losses: Goldberg (WrestleMania 20)
Recent WWE matches: Pinfall defeat to John Cena at Extreme Rules, submission victory over Triple H at SummerSlam
Achievements outside WWE: Lesnar, who trained with NFL franchise Minnesota Vikings after he left WWE in 2004, also seized the IWGP Heavyweight Championship in New Japan Pro Wrestling and won the UFC Heavyweight Championship in 2008
WrestleMania booking details
WrestleMania 29 will be shown on Sky Sports Box Office (channel 743) and in high definition on Sky Box Office HD (channel 752) at midnight on Sunday, April 7 (Mon morning).
WrestleMania 29 will be repeated on Sky Sports Box Office (channel 743) - but NOT on Sky Sports Box Office HD (channel 752) - between 10am on Monday, April 8 and 10pm on Saturday, April 13. Repeat showings will last for four hours.
The event is priced at £17.95 for UK customers, €24.95 for customers in the Republic of Ireland.
You can order WrestleMania 29 nearer the event by pressing the Box Office button on your remote. Select 'sports & events' and follow the on-screen instructions.
Viewers are able to call 08442 410 888 to book WrestleMania 29.(There may be an additional charge for telephone bookings).
You can also book WrestleMania 29 online by clicking this link www.sky.com/orderboxoffice
Cable customers should contact their local cable operator.