From winning Olympic medals and world titles to receiving widespread public acclaim and honours from the Queen, the Scot has enjoyed more than his fair share of memorable moments.
Here, Sky Sports looks back on the top 10...
1 Beijing hat-trick
Although already an Olympic champion and multiple world champion, the Beijing Games in 2008 were where Hoy transcended into the realm of British sporting legend. Great Britain dominated the boards in China, but it was Hoy's three golds in the sprint, team sprint and keirin that best epitomised the country's global superiority in track cycling. Hoy also became the first Briton in 100 years to win three golds at a single Olympics.
2 Home double
After being overlooked for Britain's sole sprint place in favour of Jason Kenny, the London 2012 Olympics had the potential to be anticlimactic for Hoy. However, he shrugged off that disappointment by helping Britain to team sprint gold alongside Kenny and Philip Hindes, before retaining his keirin crown with a superb display as GB once again reigned supreme on the track in front of an adoring home crowd.
3 Eclipsing Sir Steve Redgrave
Hoy's victory in the team sprint in London took him level with rowing great Sir Steve Redgrave on five Olympic gold medals, guaranteeing his place as one of the greatest Olympians of all time. However, he then went on to overtake Redgrave with a sixth gold in the keirin, which, in addition to his team sprint silver from Sydney 2000, took him to seven medals in total and stood him out as Britain's greatest Olympian.
4 Breakthrough gold in Athens
Legends aren't born, and their paths to greatness have to start somewhere. For Hoy, that was at the 2004 Olympic Games in Athens, when he won his first gold medal, in the 1km time trial. The achievement was given added value by the fact he broke the sea-level world record in the event in the process.
Hoy had already been awarded an MBE in 2005 following his gold medal in Athens, but was elevated to knight of the realm after his three golds in Beijing in the 2009 New Year Honour list. The accolade stood him out as one of the most successful and respected sports person in Britain.
6 Winning BBC Sports Personality of the Year in 2008
Hoy's knighthood followed quickly on from winning the prestigious BBC Sports Personality of the Year award in December 2008. He was selected by the British public ahead of then Formula One world champion Lewis Hamilton and Beijing 2008 double gold medal-winning swimmer Rebecca Adlington.
7 First world titles in Denmark 2002
Hoy joined British Cycling's sprint squad in 1996 and was winning World Championship medals from as early as 1999. However, it wasn't until the 2002 World Championships in Berlin that he announced himself as a truly top-class track cyclist, winning his first world titles in the 1km time trial and team sprint gold alongside Jamie Staff and Craig MacLean.
8 Britain's first world sprint champion in 54 years
Although already a team sprint world champion, the 1km time trial remained the event in which Hoy saw his most success. However, that changed at the World Championships in Manchester in 2008, when he became the first Briton in 54 years to win the sprint gold. Surprisingly, it would be the only world sprint title he would win in his long career.
9 Regains world keirin title in 2010
The season after the Beijing Games, Hoy was forced to miss the 2009 World Championships in Poland after picking up a hip injury in a World Cup event, and with it relinquished his keirin title. However, he bounced back the following year to regain the crown and, in process, win his 10th world title.
10 Carries TeamGB flag at London 2012
Already knighted by the Queen and a BBC Sports Personality of the Year winner, Britain's final act of recognition of Hoy's career came when he was asked to carry the Union Jack and lead TeamGB into the Olympic Stadium at the London 2012 Games. Hoy proudly carried the standard with one arm, waving it towards all corners of a raucous home crowd.