Murray, who broke his major duck at last year's US Open, is the first home winner of the prize since Fred Perry in 1936.
Here are the key milestones on the 26-year-old's path to the top.
1987: Born May 15, Dunblane, Scotland.
1999: December - Wins junior Orange Bowl title in Miami.
2004: September - Becomes first British winner of US Open boys' title, beating Ukrainian Sergiy Stakhovsky.
2005: March - Becomes youngest British Davis Cup player, aged 17, in match against Israel.
June - Defeats Radek Stepanek to become first Scot to reach third round at Wimbledon. Loses to David Nalbandian.
October - Reaches first ATP final at Thailand Open, losing to Roger Federer.
2006: February - Claims first ATP title by beating Lleyton Hewitt in San Jose.
February - Moves above Tim Henman and Greg Rusedski in rankings to become British number one.
April - Splits from coach Mark Petchey.
July - American Brad Gilbert appointed Murray's new coach.
2007: May - Snaps a tendon in his wrist at the Hamburg Masters, and the injury forces him to miss the French Open and Wimbledon.
November - Splits from coach Gilbert.
2008: July - Loses to Rafael Nadal in Wimbledon quarter-finals.
August - Defeats Novak Djokovic in Cincinnati to claim first Masters Series title.
September - Beats top seed Nadal in semi-finals of US Open to reach first grand slam final, where he loses 6-2 7-5 6-2 to defending champion Federer.
2009: June - Loses to Fernando Gonzalez in French Open quarter-finals.
June - Becomes first British player since 1938 to win Queen's Club title, beating James Blake in the final.
July - Reaches first Wimbledon semi-final but loses 6-4 4-6 7-6 7-6 to Andy Roddick.
August - Wins Montreal Masters with victory over Juan Martin Del Potro, and becomes world number two for first time.
2010: January - Loses 6-3 6-4 7-6 to Federer in Australian Open final.
July - Loses Wimbledon semi-final 6-4 7-6 6-4 to Nadal. Splits with coach Miles Maclagan after two and a half years.
2011: January - Beaten 6-4 6-2 6-3 by Djokovic in second successive Australian Open final.
June - Loses 6-4 7-5 6-4 to eventual champion Nadal in French Open semi-final.
September - Loses 6-4 6-2 3-6 6-2 to Nadal in US Open semi-final.
December - Hires eight-time grand slam winner Ivan Lendl as his new coach.
2012: January - Loses 6-3 3-6 6-7 6-1 7-5 to Djokovic in Australian Open semi-final lasting four hours and 50 minutes.
June - Murray's French Open run ends in the quarter-finals with defeat by David Ferrer.
July - Reaches Wimbledon final for the first time with victory over Jo-Wilfried Tsonga, but loses 4-6 7-5 6-3 6-4 to Federer who lands a record-equalling seventh title. Murray breaks down in tears in his on-court interview, saying: "I'm getting closer."
August - Wins Olympic gold in singles at Wimbledon by beating Federer 6-2 6-1 6-4, and takes silver in mixed doubles with Laura Robson.
September - Finally breaks his Grand Slam duck, beating Djokovic 7-6 (12/10) 7-5 2-6 3-6 6-2 to win the US Open.
December - Finishes third in the Sports Personality of the Year awards.
Awarded an OBE in the New Year Honours list.
2013: January - After beating Federer in the semi-finals, Murray loses 6-7 (2/7) 7-6 (7/3) 6-3 6-2 to Djokovic in the Australian Open final.
May - Forced to pull out of the French Open due to a back injury.
June - Wins his third AEGON Championships at Queen's Club, beating Marin Cilic in the final.
July 5 - Reaches his second Wimbledon final, beating Poland's Jerzy Janowicz 6-7 (2/7) 6-4 6-4 6-3 in the semi-finals to set up a match against world number one Djokovic.
July 7 - Triumphs in the Wimbledon men's singles with a 6-4 7-5 6-4 victory over Djokovic, becoming Britain's first winner of the title since 1936.