The 29-year-old played in the last World Cup final with Holland and has spent more than eight years in the Premier League.
But a move to Old Trafford in the summer has kept him fresh, with the Dutchman singling out the younger duo of Javier Hernandez, 24, and Danny Welbeck, 22.
"It goes both ways - I can learn from them as well," Van Persie told MUTV.
"For example, I love Chicharito's (Hernandez's) enthusiasm, I love how he plays and trains and does his work off the pitch after training.
"A couple of weeks ago he wasn't playing as much but he was in the gym every day doing extra work, and that sets a big example for everyone.
"Danny, too. He's not playing in his favourite position at the moment but we need him and he's working hard.
"When you have four strikers being so professional, it sets the tone for the others.
"Everyone realises we are all in it together and we all need to do our bit."