Though Chelsea's victory tally is superior to Villa's, the fixture has traditionally yielded a glut of goals and exhibited some thrilling attacking football from both sides.
Here are five of the best, with even Chelsea's 7-1 win in 2010 unable to make the shortlist.
1. Aston Villa 3 Chelsea 2 - April 12, 2004.
David O'Leary's Villa hosted second-placed Chelsea and came from behind to claim an unexpected victory against Claudio Ranieri's Chelsea. Hernan Crespo gave Chelsea an early lead before Darius Vassell levelled with a 39th-minute penalty.
Villa began the second half impressively and and took a 3-1 lead through quickfire goals from Thomas Hitzlsperger and Lee Hendrie. A last-minute consolation strike from Crespo could not deny the hosts a deserved 3-2 victory.
2. Chelsea 4 Aston Villa 4 - Decenber 26, 2007
This ill-tempered Boxing Day clash saw three players dismissed and eight goals shared between the two teams.
Initially, it was Villa who asserted themselves on the game. Two first-half goals from Shaun Maloney had Villa cruising towards half-time with an unlikely 2-0 lead, but a clumsy Zat Knight challenge on Michael Ballack in the Villa box saw the defender dismissed. Andriy Schevchenko's subsequent penalty made it 2-1.
Chelsea capitalised on their one-man advantage and second half goals from Schevchenko and Alex put the hosts 3-2 ahead. However, Villa skipper Martin Laursen restored parity with a 72nd-minute volley, before Chelsea themselves were reduced to ten men when Ricardo Carvalho saw red for a two-footed challenge on Gabriel Agbonlahor.
Ballack's 88th minute free-kick appeared to have secured all three points for Mourinho's Chelsea, but more drama followed. Ashley Cole became the third player to be red-carded before Gareth Barry slotted home the resultant 90th-minute penalty to salvage a point for Martin O'Neill's Villa.
3. Chelsea 3 Villa 3 - January 2, 2011
In another high-scoring draw, Gerard Houllier's Villa rescued a point with an injury-time equaliser from Ciaran Clark. This was yet another topsy-turvy meeting between the sides, which once again culminated in high drama at the final whistle .
Converted first-half penalties from Frank Lampard and Ashley Young saw the game balanced at 1-1 after 45 minutes. Villa gained the lead after 47 minutes through Emile Heskey, but Chelsea rallied and equalised through a Didier Drogba strike. John Terry then reacted quickest to a Friedel parry as he poked the ball home after 89 minutes, only for Clark to capitalise on weak Chelsea defending and head home a 91st minute leveller.
4. Chelsea 1 Villa 3 - December 31, 2011
Villa's New Year's Eve victory at the Bridge was a rare high-point of Alex McLeish's reign as Villa boss. His side were largely outplayed by Andre Villas-Boas' Chelsea, but Villa were resilient and stood firm against an attacking onslaught from the home side.
A Drogba penalty midway through the first-half gave Chelsea the lead but Stephen Ireland levelled within five minutes. Chelsea pressed all game for a winner but were frustrated by Villa's backline and fine goalkeeping from Brad Guzan.
Stiliyan Petrov struck in the 82nd minute to give Villa a surpise lead and, with Chelsea desperately seeking an equaliser, Darren Bent sealed the victory when he applied the finishing touch to a swift counter-attack.
5. Chelsea 8 Villa 0 - December 23, 2012.
In what was surely Paul Lambert's nadir last season, Villa were destroyed by Rafa Benitez's rampant Chelsea side.
Martin O'Neill's Villa team had been trounced 7-1 at Stamford Bridge back in 2010, but this was a mauling on a par with no other.
Chelsea laid siege to Villa's goal from the outset, and annihilated their opponents with a masterful attacking display. Goals from Fernando Torres, David Luiz, Branislav Ivanovic, Frank Lampard, Ramires (2), Oscar and Eden Hazard gave Chelsea an emphatic win.
In truth, the margin of Chelsea's victory could have been much higher - only the goalkeeping heroics of Guzan, who kept out Lucas Piazon's penalty kick, prevented Chelsea from achieving double figures.