The 28-year-old, who has suffered two anterior cruciate ligament injuries this season and is likely to miss all of next term, is travelling to the clinic of renowned knee specialist Dr Richard Steadman in Denver, Colorado.
Taylor tweeted on Tuesday: "All ready for my long flight to Denver tomorrow.
"Loads asking am I going to see Dr Steadman? I sure am. I'm over to have my ACL repaired again. Then the recovery begins to get back."
Taylor has made only two senior appearances this season after damaging his cruciate ligament for the first time in the Europa League qualifier second-leg match with Greek side Atromitos at St James' Park on 30 August.
Following an operation and eight months on the sidelines, he was on the verge of making a comeback when he suffered a second injury in training.
Taylor is the latest in a line of Newcastle players who have utilised the services of Dr Steadman.
He is credited with saving Alan Shearer's career and operated on Craig Bellamy before reconstructing Michael Owen's knee following the injury he suffered on England duty at the 2006 World Cup finals.