The Potters conceded two late goals in a 3-2 defeat at Old Trafford on Saturday, after twice holding the lead over Manchester United.
Stoke have only taken two points from their last six games though, and Hughes hopes his team can start a good run of results starting with the Capital Once Cup clash at Birmingham on Tuesday.
Hughes enjoyed success in the competition as a player with Manchester United, Chelsea and Blackburn, and he hopes to take Stoke all the way this season.
"We are enjoying playing at the moment but we need to get results, we can't keep patting ourselves on the back and say we are playing well we need to start winning," Hughes said.
"I've always said cup competitions can help your league form so if you get on a good run in the cup it can filter into your league form so it is an important game for us.
"We will be strong because I've always picked strong sides if you a look at the teams I've picked this year and in previous years at different clubs.
"I've always tried to give the competition the respect it deserves and we are edging towards the latter stages so why wouldn't we go strong?
"I'll make changes - some might be forced and others because I want to look at certain things - but we'll go with a team capable of winning the game.
"The competition has been quite good to me and I've always enjoyed cup competitions. I'd love to be able to take Stoke to a Wembley final. That was the aim at the start of the season.
"Birmingham are strong at home and caused an upset against Swansea so we won't take them lightly but we feel we can progress."