Rooney will return to the scene of his last sending off and the England striker is 11/4 to be booked and 33/1 to see red once again.
The Manchester United hitman is also 4/1 to outscore the whole of the Montenegro side.
bet365 spokesman Steve Freeth said: "Rooney has been on a good run in front of goal for his country, but the focus will be on how he handles himself in the hostile atmosphere of Podgorica as much as his goalscoring prowess."
Montenegro v England - Wayne Rooney Specials
To be booked 11/4
To be sent off 33/1
To score a hat-trick 28/1
Who Will Score The Most Goals?
Wayne Rooney 4/1