The 25-year-old is out of contract at Orient at the end of the season and no new deal has been agreed as yet.
The news has alerted a host of Championship and League One clubs to Omozusi's possible availability on a free transfer this summer.
Omozusi has been a stand-out performer for Orient since rejoining the club in January 2013 and has been instrumental in their push for promotion from League One this season.
The full-back has made 46 appearances for Orient in all competitions this season and established himself as a key member of Russell Slade's side.
The likes of Reading, Brighton and Bristol City are all thought to be monitoring Omozusi's contract situation at Brisbane Road, with Orient keen to tie him down to a new deal.
Sources close to Omozusi claim the player is putting talk over his future on the backburner as he focuses on trying to win promotion via the play-offs.