Dos Santos, the younger brother of former Tottenham attacker Giovani, has struggled to make an impression on the first team at Camp Nou.
The Mexico international has been linked with Everton and West Ham United, and playing in England appeals to the 22-year-old.
"If I leave Barcelona, my preferred destination is the Premier League," Dos Santos told RAC1.
He has acknowledged his frustration at failing to play regularly for Barcelona, but he believes he is benefiting from the experience of being with Tito Vilanova's squad.
Dos Santos added: "I am not content with just a few minutes of game time, but this Barcelona squad is incredible and I am learning a lot with this experience.
"Really, I am not sorry to have stayed at the club because we are the best in the world."