Tendayi Darikwa's 47th-minute goal proved decisive as the Derbyshire side took their haul to five wins and a draw from their first six games.
Oxford maintained their momentum with a 2-0 win at Burton, moving above their hosts into second place.
Burton were reduced to 10 men in the 36th minute when Ian Sharps was dismissed and the visitors capitalised in the second half with goals from Alfie Potter (49) and Danny Rose (85).
A goal in each half from Michael Smith gave AFC Wimbledon a 2-0 win at struggling York which lifts them to third.
Fourth-placed Fleetwood brushed aside Torquay, with goals from Antoni Sarcevic (10 and 37), Jamille Matt (62) and Matty Blair (90) giving them a 4-1 home win. Elliott Benyon (89) replied.
Hartlepool scored their first goal of the league campaign, through James Poole - but it came in the last minute and Max Kretzschmar (51 and 69) had already netted twice for visitors Wycombe.
Morecambe came from behind to surprise Southend 3-1 at Roots Hall and climb into the top seven.
The Essex side took the lead through Kevan Hurst's goal on the half hour but Andrew Fleming (35 and 47) and Jack Sampson (56) turned things around, before the visitors had Robbie Threlfall dismissed.
Plymouth moved into the top half as Reuben Reid's 82nd-minute goal saw off Bristol Rovers - and 1-0 was also the scoreline at Spotland, where Scott Hogan's 36th-minute breakthrough earned a win for Rochdale - who had Peter Vincenti sent off soon after the goal - against Bury.
Portsmouth have won just one of their first six games after Cheltenham's Jermaine McGlashan twice pegged them back at Whaddon Road.
Patrick Agyemang gave Pompey a fifth minute lead, McGlashan levelled in the 36th, only for Johnny Ertl to restore the visitors' lead a minute before half-time. However, McGlashan scored in injury time to deprive the pre-season title favourites of victory.
Josh Scott gave Dagenham & Redbridge a 20th-minute lead against Exeter but the fifth-placed Grecians earned a point through Sam Parkin's goal 10 minutes from time.
League newcomers Newport and Mansfield shared two goals and two sendings off at Rodney Parade.
Chris Zebroski headed the hosts into the lead after half an hour but Sam Clucas levelled for Mansfield midway through the second half. Newport had Lee Minshull sent off 14 minutes from time, with the Stags' Matt Rhead following soon after.
The other game also finished 1-1, with Niall Canavan giving Scunthorpe the lead midway through the second half at Northampton, only for the winless Cobblers to earn a point through Clive Platt's 78th minute breakthrough.