Jack Wilshere struck the crossbar early on as Arsenal enjoyed the better of the game before taking the lead on 29 minutes through their Cardiff old boy.
Mesut Ozil curled in a cross from the left and Ramsey's run into the box was not tracked as the Wales international flicked his header beyond David Marshall.
Fraizer Campbell's downward header produced a superb one-handed save from Wojciech Szczesny before Arsenal made the game safe with four minutes to go when Ozil slipped in Mathieu Flamini for a thumping finish beyond Marshall.
In added time, Ramsey scored his second of the game as he angled a shot just inside the frame of the goal after being set up by Theo Walcott.
After a tight first half, West Ham took the lead two minutes after the break when Mohamed Diame won possession from Steve Sidwell before his 25-yard shot took a deflection to leave Maarten Stekelenburg wrong-footed.
West Ham wrapped up the points eight minutes from time when Stewart Downing was played in on the right of the box and his teasing low cross was converted by Cole at the far post.
Fulham's miserable afternoon was capped on 89 minutes when Ravel Morrison got down the left and cut into the box before teeing up fellow substitute Joe Cole for a drilled finish from the edge of the area.
Norwich went ahead on the half-hour mark following a penetrating run down the right by Nathan Redmond before the ball was worked to Hooper, who had time to take a touch on the edge of the six-yard box before side-footing home.
Stoke keeper Asmir Begovic had been a one-man barrier in the first half until the visitors' resistance was broken in the final minute when Deulofeu exchanged passes with Steven Pienaar and Gareth Barry before lashing home a left-footed shot.
Deulofeu turned provider for Everton's second goal four minutes after half-time when his cross from the left found its way to Seamus Coleman, who sliced a left-footed volley past Begovic.
A third goal arrived before the hour mark when Bryan Oviedo, who replaced the injured Leighton Baines at left-back, cut inside on his right foot and fired a low 25-yard shot inside the post.
Everton were in rampant mood and scored a fourth goal on 79 minutes when Leon Osman played in Oviedo down the left and the Costa Rican's low cross into the six-yard box was finished by Romelu Lukaku.
Sunderland enjoyed the better first-half chances as Craig Gardner had a goal correctly ruled out for offside before Emanuele Giaccherini scooped the ball over the bar after being found unmarked just four yards out.
Alan Pardew's side took the lead on 36 minutes when West Brom keeper Boaz Myhill's poor punch from Yohan Cabaye's corner flew into the air and Yoan Gouffran nodded into an unguarded net.
West Brom rallied in the second half and equalised on 54 minutes when Chris Brunt rifled past Tim Krul at the far post after a cross from the right had been allowed to reach the Northern Ireland winger.
But, just three minutes later, Newcastle scored the winner when Loic Remy headed the ball into Sissoko's path and the midfielder's swerving 25-yard shot flew into the top corner.