Hull City v Chelsea, 12.45pm
Key stat: Hull City last defeated Chelsea in October 1988 and have gone nine meetings since without a win against the Blues (L7 D2).
Hull boss Steve Bruce is hopeful that a sickness bug that has swept through the Tigers camp will not keep out too many players, while Chelsea remain without Branislav Ivanovic and Frank Lampard. Read full Hull v Chelsea preview.
Cardiff City v West Ham United
Key stat: West Ham have won their last five meetings with Cardiff City in all competitions, keeping four clean sheets in the process.
Andy Carroll could make his long-awaited return for West Ham, while Cardiff have Craig Bellamy available again and should hand a debut to Magnus Wolff Eikrem. Read full Cardiff v West Ham preview.
Everton v Norwich
Key stat: Everton are without a win in five Premier League meetings with Norwich (D4 L1).
Ross Barkley and Leighton Baines are among four injury concerns for Everton, but Norwich welcome back Leroy Fer, along with the players rested for last weekend's FA Cup tie. Read full Everton v Norwich preview.
Fulham v Sunderland
Key stat: Fulham have kept six clean sheets in their last nine Premier League meetings with Sunderland (W4 D4 L1).
Clint Dempsey and Darren Bent will hope to keep their places for Fulham after impressing in the FA Cup, while Sunderland may name the same side that beat Manchester United in the Capital One Cup in midweek. Read full Fulham v Sunderland preview.
Southampton v West Bromwich Albion
Key stat: Saints have lost six of their last nine in the Premier League; winning just once (D2). West Brom are unbeaten since Steve Clarke was sacked (W1 D3).
Southampton could welcome back Artur Boruc but remain without Victor Wanyama and Dani Osvaldo, while Keith Downing will have to make do without Billy Jones and Goran Popov at least for his final game in caretaker charge of West Brom. Read full Southampton v West Brom preview.
Tottenham Hotspur v Crystal Palace
Key stat: Tottenham have scored nine goals in four league games under Tim Sherwood. Since Tony Pulis has taken over, Palace have conceded just eight goals in eight league games.
Tottenham boss Tim Sherwood remains without a host of players for the club's 200th London derby in the Premier League, but Palace are hopeful that Cameron Jerome will be fit to return up front. Read full Tottenham v Crystal Palace preview.
Manchester United v Swansea City, 5.30pm
Key stat: United have averaged more points per game in January (2.28) than any other team in Premier League history.
United look set to be without Wayne Rooney and Robin van Persie again, while Swansea have seen Jonathan de Guzman and Dwight Tiendalli added to their lengthy list of injured players ahead of the game. Read full Manchester United v Swansea preview.
Newcastle United v Manchester City, Sunday, 2.05pm
Key stat: City have scored at least twice in each of their last 11 league meetings with Newcastle.
Tim Krul and Yohan Cabaye could return to the Newcastle starting line-up, but Manchester City remain without Sergio Aguero among others, and have a doubt over Yaya Toure. Read full Newcastle v Manchester City preview.
Stoke City v Liverpool
Key stat: Stoke have won three and lost none of their five previous Premier League home meetings with Liverpool (D2), winning the last three in a row.
Third-choice Jack Butland will make his first Premier League start for Stoke, who also have injuries to contend with in the outfield positions, while Liverpool will be without Daniel Agger but should have Daniel Sturridge back available. Read full Stoke v Liverpool preview.