The Grecians lost the Devon derby 1-0 against Plymouth and suffered a last minute 2-1 defeat to Rochdale.
However, Tisdale's side remain in the top six, three points clear of seventh-placed Fleetwood, and have a game in hand over their promotion rivals.
"We've had two terribly disappointing days, but there's no point crying over it," Tisdale told BBC Radio Devon.
"We lost the games, but we're still in the play-off zone, we're in a good position and it's about the next game."
It is the first time City have suffered successive defeats since October but Tisdale is backing his players to respond in the right manner.
"I'm asking a lot of certain players, but I have to back them, we have to back each other," he added.
"The players and I will give everything we can to get us over the line and into the play-offs."