The 63-year-old Italian, along with Bernie Ecclestone, helped to run Rangers for three years during which time nine different people were in charge of first-team affairs at Loftus Road.
These were Luigi De Canio, Iain Dowie, Paulo Sousa, Gareth Ainsworth, Jim Magilton, Steve Gallen, Paul Hart, Mick Harford and Neil Warnock.
Briatore, a former managing director at motorsport team Benetton, told F1 Racing magazine: "If you don't fire these coaches, you never go up.
"When you understand someone is not good enough to do the job, it is better you fire them immediately rather than waste another six months.
"I felt we were going nowhere with these guys. In the end, we made it. The most important thing in sport is the result.
"We took QPR from the bottom of the Championship.
"There was a four-year plan and we took them into the Premier League. I don't understand the fuss. We did it with not much money.
"After Bernie and I went away leaving Mr Lakshmi Mittal and Mr Tony Fernandes to run the show, and spend a lot of money, it's funny to see they still have six or seven players who were with us in the Championship.
"I believe we did it quite well but, I tell you, it was no fun at all. You need to treat football like a full-time job and not like an investor.
"There were too many people. The manager, the assistant manager and, always, you were dealing with the agents. In the end, we sold it."