The Sky Blues finished the match with nine of the 11 players on the pitch having come through the club's academy as Josh McQuoid's goal decided a close encounter at Adams Park.
Pressley's side now go into their return to the Ricoh Arena on the back of a victory and he said: "In terms of the fluency of our football I don't think it was brilliant.
"That is credit to Wycombe who really pressed us and forced us into making mistakes at times but ultimately football is about winning games and getting results.
"Coming here with such a young squad and getting a win is a terrific result for us.
"Eleven of our 16 players are academy-based players and nine from the 11 that finished the game is probably a record for Coventry City, which is outstanding.
"This is only the start of a long-term project and I'm proud of how they're adapting and I'm proud of their work-rate.
"They put us under a lot of pressure in the second half but our three central defenders were excellent.
"Overall I'm really proud - not a vintage performance with the fluency that I like to see but in terms of commitment we were excellent."
The only goal arrived after 66 minutes when Danny Swanson picked out Danny Pugh on the left and his excellent cross was lashed in at the back post by McQuoid.
The closest a dogged Wycombe came to forcing an equaliser was when Aaron Pierre headed Danny Rowe's corner against the crossbar.
Boss Gareth Ainsworth said: "We got a great reaction at the end of the game from our fans because I think they know that there was only one team in that game.
"The Coventry staff have come in and reiterated that comment to me and I thought we were superb.
"The only thing was sticking it in the back of the net, which has eluded us, but I really was impressed with the performance and that's what's important to me.
"Some of the boys who have come in like Matt Bloomfield, Stuart Lewis - ones who have been on the side waiting for their chance - have come in and done brilliantly.
"Big Aaron Holloway up front has given us a glimpse of what he can be and I'm just really proud.
"The work-rate was something special and if we keep doing that and keep playing how we are then we'll have a much better season than last year."