Reports are connecting the 23-year-old Brazil international, who only missed the 2012 Olympics due to injury, with a move to Europe.
And, after featuring in Santos' victory over Atletico Mineiro on Wednesday, Rafael confesses his future is uncertain.
He told Globo Esporte: "I honestly don't know if this was my last game [for Santos]. But let's see."
Santos have yet to receive an official approach from either Walter Mazzarri's Inter or Roma but vice-president Odilio Rodrigues has indicated they would listen to offers.
"We know that those clubs are interested but we have received no offers," said Rodrigues. "We heard about the interest but we have received nothing.
"We often receive offers, he is a player we trust a lot. If an offer comes, we will analyse it."