Dennis Aogo scored one and set up another as Hamburg beat their northern German rivals, nine-man Werder Bremen 3-2 to collect their first victory of 2013.
Assani Lukimya gave Bremen the lead after nine minutes before Heung-Min Son equalised in the 22nd minute. Aogo pushed Hamburg ahead in the 46th and Artjoms Rudnevs made it 3-1 after 52 minutes.
Sokratis Papastathopoulos pulled a goal back for Bremen in the 54th minute before Werder captain Clemens Fritz was sent off after receiving a second yellow in the 80th minute. The visitor's numbers were further reduced in injury time after Marko Arnautovic also saw red.
Mario Mandzukic scored one and set up another as runaway leaders Bayern Munich increased their lead at the top to 11 points with a 2-0 victory at Stuttgart.
Mandzukic gave Bayern the lead in the 50th minute before Thomas Muller made it two inside the final 20 minutes.
Stuttgart played the final 10 minutes a man light after Martin Harnik was shown a second yellow card.
Bayer Leverkusen regained second place in the Bundesliga on Saturday, but failed to reduce the arrears on Bayern Munich to six points as they came away with just a point from a 0-0 draw at Freiburg.
In an open, entertaining game at the Dreisamstadion, hosts Freiburg did justice to their own high league position by putting Leverkusen on the ropes several times.
Leverkusen also created chances with the only real surprise being the game finishing in a goalless draw, which gives Bayern the chance to extend their advantage at the top to 11 points when they face Stuttgart on Sunday.
Elsewhere on Saturday, Hoffenheim slumped into the bottom two of the Bundesliga after being beaten 2-1 by an Eintracht Frankfurt side who remain on course for a place in Europe next season.
Frankfurt completed the double over their visitors thanks to goals from Martin Lanig and Stefan Aigner with Kevin Volland bringing Hoffenheim level in between.
Schalke failed to build on their win over Hannover last weekend as they were lucky to get a point from their trip to struggling Augsburg, who had the better chances in a goalless draw in Bavaria.
Mainz further reduced Greuther Furth's dwindling hopes of playing a second season in the Bundesliga with a convincing 3-0 win at the Furth Arena.
Two goals from Adam Szalai and a Yunus Malli strike earned Thomas Tuchel's side all three points as Furth - winless at home this season - fell apart in the second half.
The Bavarians held their own during the first 45 minutes but never looked close to landing an historic first home win in the Bundesliga and remained rooted to the foot of the table on just nine points from 19 matches.
Borussia Monchengladbach picked up their first three points of 2013 with a 2-1 victory in the Rhine derby against Fortuna Dusseldorf, who lost their second game in a row.
An own goal from Juanan and a Patrick Herrmann strike gave the Foals a two-goal lead at half time.
A penalty from Dani Schahin gave Fortuna hope early in the second half, but they were unable to find an equaliser as the home side played down the clock without running too much risk of conceding.
First-half goals from Mohammed Abdellaoue and Mame Diouf proved decisive at the Niedersachsenstadion as 10-man Hannover held on for three points in the Lower Saxony derby against a luckless Wolfsburg.
The Reds had new signing Sebastien Pocognoli sent off in the 34th minute and were on the ropes after Alexander Madlung halved the deficit for the visitors in the first minute of the second half.
But, despite their best efforts, the Wolves were unable to find an equaliser.
On Saturday, Borussia Dortmund had moved up to second thanks to a comfortable 3-0 win over Nurnberg.
Jakub Blaszczykowski scored twice in the first 21 minutes but Jurgen Klopp's men had to wait until the 88th minute before being assured of the points, when Robert Lewandowski made it three.
The result was rarely in doubt, though, as Dortmund dominated from start to finish, struggling only to find the back of the net more frequently.