Lyon were unable to pick up the win they needed to move level with Paris St Germain at the top of Ligue 1 after drawing 1-1 at Brest on Sunday.
Kamel Chafni gave the strugglers an eighth-minute lead, only for Tripy Makonda's own goal eight minutes into the second half to earn Remi Garde's visitors a point.
The draw means Lyon trail PSG by two points while Brest move five points clear of the bottom three.
The Parisiens suffered a surprise setback on Saturday as they slumped to a 1-0 defeat away to the 10 men of relegation-battling Reims.
Zlatan Ibrahimovic had a goal controversially disallowed early in the second half, and Reims then had Christopher Glombard sent off for a second bookable offence before the hour mark.
But Reims still ran out winners as Grzegorz Krychowiak scored the only goal in the 64th minute.
Marseille did take advantage of PSG's slip-up as Andre-Pierre Gignac's late goal earned them a 2-1 win against bottom club Troyes.
Brazilian striker Marco had given the visitors the lead in the 71st minute as they sought would have been just a fourth win of the season.
However, a Florian Jarjat own goal levelled the scores with nine minutes left and, buoyed by the equaliser, Gignac struck a minute later to seal the points and move them to within five points of the summit.
Lille battled from a goal down to maintain their European push with a hard-fought 2-1 victory over Bordeaux at the Grand Stade Lille Metropole this evening.
Les Girondins headed into the game looking to arrest a three-game losing run, and took the lead through a Jaroslav Plasil penalty just after the half-hour mark.
But Rudi Garcia's side responded well and turned the game on its head thanks to second-half goals from Ronny Rodelin and Salomon Kalou to secure their fourth straight league win and climb to seventh in the standings.
Nice paid the price for the first-half dismissal of Valentin Eysseric as St Etienne continued their push for Champions League football next season with an emphatic 4-0 win.
St Etienne led early on through Pierre-Emerick Aubameyang's penalty but the game turned on the 23rd-minute dismissal of Eysseric, whose ugly challenge on Jeremy Clement spelled the end of the night for both men.
Nice held out with 10 men until the break only for the floodgates to open in the second half, with Yohan Mollo scoring in between Brandao's brace.
St Etienne remain undefeated in 2013 as a result.
Toifilou Maoulida scored the only goal as Bastia beat Ajaccio 1-0 in a fiery Corsican derby but it was the dismissals of five players, four in the final minute, which will create the headlines.
Maoulida struck early in the second half with Ajaccio's hopes of a comeback not helped by a second yellow card for Mathieu Chalme 10 minutes from time.
However, the match was overshadowed by events in the dying moments when Dennis Oliech's dismissal for the visitors sparked a brawl which resulted in subsequent red cards for team-mate Benjamin Andre and Bastia duo Florian Thauvin and Jerome Rothen.
Nancy climbed off the bottom after upsetting Sochaux 2-1 to claim only their fourth win of the season.
First-half goals from Benjamin Moukandjo and Florent Zitte put Nancy in charge, and Sochaux halved the deficit through Sloan Privat's acrobatic effort in stoppage time at the end of the game.
Gael Danic's 79th-minute penalty ensured Valenciennes claimed a 1-1 draw at Lorient.
Danic slotted home from the spot late on after Lorient defender Arnaud Le Lan had handled in the area.
The hosts had taken a third-minute lead through Kevin Monnet-Paquet's low strike, their first chance of the game, but Le Lan's error cost them dear.
Meanwhile Evian were left three points short of safety at the foot of the table after a goalless draw at Toulouse which did little to set the pulses racing.
On Friday night, Montpellier boosted their European hopes as they beat Rennes 2-0.
The in-form La Paillade recorded their eighth consecutive home win in Ligue 1 thanks to two late second-half goals from Vitorino Hilton and Souleymane Camara.