This match last season at the Cottage was famous not only for Fulham's 6-0 drubbing of the Hoops but also Adel Taarabt being substituted at half-time and then storming out and waiting for a bus in his tracksuit in disgust at former manager Neil Warnock's fresh tactical approach.
Warnock is long gone and the mercurial Moroccan still falls in and out of favour under Harry Redknap but the visitors are fancied to boost their survival prospects with a valuable three points from the short journey across west London.
They remain rooted to the foot of the table and seven points from safety before Saturday's games kicked off but they are playing as well as at any time of the season and Redknapp remains optimistic he can pull off another famous great escape.
"It is up to us," was his succinct assessment with the points on offer from eight remaining games looking more than enough to make a horserace of it.
QPR were certainly on the generous side last time when they allowed fellow strugglers Aston Villa to escape with a 3-2 victory as Redknapp fumed at his team for not being four up and out of sight at the break.
But the influx since the new year of the likes of Loic Remy, Andros Townsend and a resurgent Jermaine Jenas (two goals in his last two games) have overall given Rangers some impetus as they try and rescue themselves from a return to the Championship.
It is a case of the same old, same old for Fulham.
They are a solid enough Premier League outfit capable of the odd flash of something worth watching - usually inspired by Dimitar Berbatov.
But once again they find themselves playing for little more than a top-10 finish between now and the end of the campaign, although a stretch of four games unbeaten is creditable.
The visitors have won just once against Fulham from their last seven encounters but I have seen enough of late from them to reverse that trend.
This is exactly the sort of fixture Redknapp knows he must win if they are to have any chance in the grand scheme of things and a small investment on them is the play.