Manchester City have been cut to 14/1 with Sky Bet to win Champions League after they booked their place in the knockout stages following Tuesday night's 5-2 victory over CSKA Moscow.
Manchester United edged a little closer to the last 16 following a goalless draw at Real Sociedad in which Robin van Persie missed a penalty and Marouane Fellaini was sent off.
David Moyes' men are top of Group A and three points clear of third-placed Shakhtar Donetsk but their odds to lift the trophy have drifted out to 16/1.
The 11/4 tournament favourites remain Bayern Munich, who also sealed their progress from City's group following a 1-0 victory in Plzen, while Barcelona and Real Madrid are next in the running at 9/2 and 5/1 respectively.
Chelsea are Arsenal are both in action on Wednesday night and can be backed at 14/1 and 20/1 to go all the way in Europe's premier competition this season.