The Blues will welcome the Tigers to Stamford Bridge on August 17, with Mourinho set to take centre stage on his return to English football.
A trip to Manchester United on the second weekend of the campaign could offer an early indication as to the destiny of the league crown, with fireworks to be expected at Old Trafford.
Chelsea will take in back-to-back London derbies in September, with a home date with Fulham followed by a visit to Tottenham Hotspur - which will see Mourinho pitched head-to-head with his former assistant Andre Villas-Boas.
It promises to be an intriguing festive period for the Blues and they will want to build momentum during an away date at Arsenal on December 21 for battles at the Bridge with Swansea City on Boxing Day and Liverpool on December 28.
Manchester United will travel to west London on 18th January, while Mourinho will take his troops to Manchester City on 1st February and Liverpool on April 26.
Chelsea will bring the curtain down on their season with a home clash with Norwich City and a trip to Cardiff City on the final weekend.