Zinedine Zidane made a winning start to his managerial career in the Champions League as a 2-0 victory in the Italian capital put Real Madrid firmly in control of their last-16 clash against Roma.
A game that had been cagey in the first half opened up in the second, and Cristiano Ronaldo broke the deadlock in the 57th minute.
Both teams had a number of chances after that but it was Real who took advantage, with 22-year-old substitute Jese scoring his first Champions League goal four minutes from time.
Gent gave themselves a lifeline with two late goals in a 3-2 home defeat by Wolfsburg.
Neither side had ever made the knock-out stages before but Wolfsburg went into the tie as favourites and lived up to their billing as they cruised into a three-goal lead.
Julian Draxler was Gent’s tormentor in chief, the 22-year-old scoring twice before Max Kruse added a third.
But the game changed with Sven Kums’ goal 10 minutes from time, and Kalifa Coulibaly then pulled another one back to make the second leg far from the formality it had appeared.