Manchester United will host fierce rivals Manchester City in the fourth round of the League Cup.
Jose Mourinho and Pep Guardiola will resume their battle, which turned extremely sour in Spain when they were in charge of Real Madrid and Barcelona, while the Spaniard claimed the early bragging rights with a derby victory in the Premier League earlier this month.
And now the pair will clash again when holders City visit Old Trafford in the week of October 24.
The Manchester derby was not the only heavyweight tie, with Liverpool and Tottenham also set to do battle for a place in the quarter-finals.
Meanwhile, there will be a London derby between West Ham and Chelsea, who won a dramatic third-round tie against Leicester in extra-time on Tuesday.
Norwich’s reward for beating Everton at Goodison Park is a trip to Elland Road to face Leeds while Preston, who took the Premier League scalp of Bournemouth, will travel to Newcastle.
Arsenal host Reading while Hull travel to the south west to face Bristol City and there is an all-Premier League clash between Southampton and Sunderland.
West Ham v Chelsea
Manchester United v Manchester City
Arsenal v Reading
Liverpool v Tottenham
Bristol City v Hull City
Leeds United v Norwich City
Newcastle United v Preston North End
Southampton v Sunderland